Cefaly vs Nerivio vs Migraelief: Which Device is Best for Migraines?

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Cefaly vs. Nerivio vs. Migraelief: Which Device is Best for Migraines

This article was reviewed and approved by Bramhansh's Scientific Consultants Team.

In this blog, we will compare three popular migraine relief devices: Cefaly vs Nerivio vs Migraelief. When it comes to choosing the best device for migraine treatment, Cefaly, Nerivio, and Migraelief are all viable options with their unique advantages and potential side effects.

Migraines are a prevalent neurological condition that affects millions of individuals worldwide. Finding an effective treatment can be challenging, but advancements in technology have led to the development of innovative devices specifically designed for migraine management.

Each device offers a unique approach to managing migraines, and by understanding their differences, readers can make an informed decision with evidence to help the readers to make an informed decision about which device may be the best fit for their needs. Let's take a closer look at each device's overview and its associated side effects to determine which one may be the most suitable choice.

How important is it to find a device that is comfortable to use?

Finding a device that is comfortable to use is crucial in migraine treatment. Migraine sufferers often experience heightened sensitivity to sensory stimuli, including touch and pressure. Therefore, a comfortable device can significantly enhance the overall treatment experience and compliance. When a device is comfortable, it reduces the risk of causing additional discomfort or exacerbating migraine symptoms during use. It ensures the device can be worn or applied for the recommended duration without causing undue strain or irritation.

What is the role of neuromodulation in migraine treatment?

Neuromodulation plays a significant role in migraine treatment by using techniques that target and modify the neural pathways involved in migraine episodes. This approach offers non-invasive and drug-free options for managing and reducing the frequency and intensity of migraines. Techniques such as transcutaneous electrical nerve stimulation (TENS), occipital nerve stimulation (ONS), and vagus nerve stimulation (VNS) are commonly employed.

These techniques work by altering the electrical signals within the nerves or brain regions associated with migraines, thereby providing relief and improving the quality of life for migraine sufferers. Neuromodulation techniques have shown promising results in reducing migraine frequency and severity, offering an alternative or complementary approach to traditional medication-based treatments.


Cefaly is a neurostimulation device designed to manage migraines through gentle electrical stimulation. It involves placing a small electrode on the forehead, which emits electrical impulses. These impulses specifically target the trigeminal nerve, which plays a role in migraine pain. By modulating the activity of this nerve, Cefaly aims to reduce the frequency and intensity of migraines, providing relief from symptoms and preventing future attacks.


When it comes to side effects, Cefaly is generally safe and well-tolerated. The most common side effect is a mild tingling or itching sensation at the site where the electrode is placed. This sensation is temporary and typically disappears during or after treatment. In rare cases, some individuals may experience minor skin irritation or redness at the electrode site. To minimize the risk of such irritation, it's important to follow the manufacturer's instructions carefully and ensure proper placement of the electrode.


Nerivio is a device that utilizes neuromodulation technology for migraine treatment. It works by delivering a controlled electrical signal to the nerves in the upper arm. When a migraine occurs, the device is placed on the arm and activated through a smartphone app. The electrical signal stimulates the arm nerves, which then send signals to the brain to regulate the pain pathways involved in migraines, providing relief from symptoms. Nerivio is designed for home use, offering convenience for individuals managing their migraines.


Regarding side effects, Nerivio is generally well-tolerated. Some users may experience a mild tingling or pulsating sensation at the application site on the arm, which is temporary and tends to subside after treatment. In rare cases, there may be skin redness or irritation at the application site.

Following the manufacturer's instructions for proper usage can help minimize the risk of any potential side effects. If you have any concerns or experience unusual side effects while using Nerivio, it's important to consult with your healthcare provider. They can provide personalized guidance based on your specific situation and determine if Nerivio is a suitable option for you.


MIGRAELIEF is a medical-grade device that has been specifically developed to assist individuals who have not found relief for their migraine symptoms through other treatments. It utilizes low-frequency sound waves, and its distinctive band design and transducer placement ensure the efficient distribution of wave energy throughout the head.


The waves produced by the transducer interact and create patterns along the band, effectively transmitting these low-frequency waves to cells, tissues, and bones. This stimulation targets the trigeminal and occipital nerves in the brain, triggering a natural relaxation response in the body to alleviate pain and promote sleep.

The MIGRAELIEF device is worn like a headband and should be positioned at the center of the forehead. A 20-minute treatment session with the device has been found to reduce migraine pain. Additionally, MIGRAELIEF can be easily managed through the MIGRAELIEF app, allowing individuals to personalize their treatments and track their migraines. The app includes a dedicated migraine record, which can be shared with healthcare providers to facilitate better management of migraines.

The device has shown promising results, with an 82% response rate. This indicates that over three-fourths of users reported falling asleep within 20 minutes of device usage, and more than 70% experienced immediate relief from acute migraine headache pain after just 20 minutes of use. From the users' perspective, these results have been instrumental in reducing severe work impairment and helping them return to their regular routines.

Comparison of Devices:


When it comes to effectiveness, all three devices have shown promising results in reducing migraine frequency, severity, and duration. Clinical studies have demonstrated the efficacy of Cefaly, Nerivio, and Migraelief in migraine management. However, individual responses may vary, and it is essential to consider personal preferences and treatment goals. Consulting with healthcare professionals can provide valuable insights into which device may be more effective for your specific migraine patterns.

Side Effects:

Considering potential side effects is crucial when choosing a migraine device. Cefaly and Nerivio generally have minimal side effects, such as tingling sensations or skin irritation at the application site. These effects are usually temporary and well-tolerated by most users. On the other hand, Migraelief, being a non-invasive device, has no known major side effects. However, individual sensitivities may vary, and it is advisable to carefully read the device's instructions and consult healthcare professionals if any concerns arise.


The cost of migraine devices can vary and is an important consideration. While all three devices require a one-time purchase, there are additional expenses associated with Cefaly and Nerivio. Cefaly requires costs for electrode replacement over time, and Nerivio involves ongoing expenses for disposable parts. In contrast, Migraelief does not have any additional charges for replaceable or disposable parts. Therefore, Migraelief is a more cost-effective option compared to Cefaly and Nerivio.


Convenience plays a vital role in device usability and integration into daily life. Cefaly and Migraelief are wearable devices that can be used at home or on the go, offering flexibility and convenience. Migraelief, which is applied to the forehead, provides portability and is easy to use to track your migraine attack with the Migraelief App. Consider factors such as device size, portability, and how well the device aligns with your lifestyle and preferences.

Other Factors:

Additional factors important to readers may include device features, customization options for treatment, customer support, and the availability of clinical evidence supporting each device's efficacy. These factors can vary among the devices and may influence your decision-making process.

How to get insurance coverage for a migraine device?

To obtain insurance coverage for a migraine device, follow these steps:

1. Review your insurance policy to understand the coverage for medical devices and migraine treatment.

2. Consult your healthcare provider to discuss the benefits of using a specific device and obtain a written prescription.

3. Contact your insurance company to inquire about coverage requirements and necessary documentation.

4. Submit the required documents, including the prescription and supporting medical documentation.

5. Follow up with the insurance company and provide any additional information they may request.

6. Advocate for coverage and address any concerns or denials through the appeal process if needed.

Remember to be proactive, communicate with your healthcare provider, and follow the insurance company's procedures to increase your chances of obtaining coverage for the migraine device.


Considering the overview and potential side effects of these devices, Migraelief distinguishes itself as a superior choice among Cefaly and Nerivio for migraine treatment. This is primarily due to its minimal side effects, natural approach, and the added benefit of the Migraelief app, which helps track migraine attacks. Migraelief presents an alternative that has the potential to provide relief to migraine sufferers without significant discomfort or adverse reactions. The absence of major side effects further enhances its appeal as a safe and gentle treatment option.

However, it's important to acknowledge that the effectiveness and personal preference for a particular device can vary among individuals. Therefore, it is crucial to consult with healthcare professionals to make an informed decision based on individual preferences and treatment goals.

Frequently Asked Questions

Q: How do these devices work?

Cefaly and Nerivio work by modulating nerve activity to reduce the frequency and intensity of migraines. Cefaly stimulates the nerves in the forehead, while Nerivio stimulates the nerves in the arm. Migraelief utilizes sound therapy to provide relief from migraine symptoms.

Q: Are these devices effective in treating migraines?

All three devices have shown effectiveness in managing migraines, although individual results may vary. It's important to consult with a healthcare professional to determine which device may be the most suitable for your specific condition.

Q: What are the side effects of these devices?

Cefaly is generally safe and well-tolerated, with the most common side effects being a mild tingling or itching sensation at the electrode site. Nerivio may cause a temporary tingling or pulsating sensation at the application site. Migraelief is generally well-tolerated, and there are no known major side effects associated with its use.

Q: How much do these devices cost?

The cost of these devices may vary. It's advisable to check with the manufacturers or consult your healthcare provider for information on pricing and potential insurance coverage.

Q: Which device is more convenient to use?

Cefaly, Nerivio, and Migraelief offer different levels of convenience. Cefaly and Nerivio can be used at home, while Migraelief can be used anytime and anywhere. The convenience factor may depend on individual preferences and lifestyle.

Q: Can these devices be used alongside medication?

It's important to consult with a healthcare professional regarding the use of these devices alongside medication. They can guide the appropriate treatment plan for managing migraines based on your specific needs.

Q: How can I determine which device is best for me?

Choosing the best device depends on individual preferences, medical history, and the advice of a healthcare professional. It's recommended to discuss your options with a healthcare provider who can evaluate your specific condition and help you make an informed decision.

EfficacyReduces acute migraine headache pain and other symptoms, and improves sleep quality within 20 minutes.reduces migraine intensity, duration, and associated symptoms.Decrease in migraine days per month and medication intake.
Pricing INR 14,999 (one-time pricing)$599 + additional cost for parts€369 + additional charges for electrodes
Working PrincipleBone conductive low-frequency  sound stimulationElectrical stimulationElectrical stimulation
User FriendlinessIt is highly user-friendly with its headband design which is easy to wear and position on the forehead, with minimal effort for setup and operation.It requires placement on the upper arm and activation using a smartphone app. While the app interface may require some familiarity.It involves placing an electrode on the forehead, which may require some initial adjustment and positioning.
Additional CostNo additional chargesIt has ongoing expenses of $49 for disposable parts. Requires additional cost of $25 - $33 for electrode replacement over time.
Side EffectsNo significant reported adverse events.Mild tingling or pulsating sensation at the application site, and rarely, skin redness or irritation. Mild tingling or itching sensation at the electrode site, and rare cases of minor skin irritation or redness.

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